What are macro-aspirations associated with?

Macro-aspirations are associated with non-infectious lung inflammation primarily because they involve the inhalation of substances that can irritate the lung tissues, leading to inflammation. This can occur when large volumes of liquids, foods, or other materials enter the airways and lungs, which do not necessarily carry pathogens. Such aspiration can cause swelling, redness, and other signs of inflammation in the lung tissues, even if there is no bacterial infection involved.

Understanding the context of macro-aspiration is crucial because while it can lead to infectious complications, its immediate effect is on the lung's inflammatory response. In this scenario, non-infectious lung inflammation would be a primary concern, as the body reacts to the introduced substance. Infections, such as pneumonia, generally stem from micro-aspirations where pathogens enter the lungs, often leading to bacterial pneumonia, which is a distinct process from the inflammatory response triggered by large volume aspirations.