What protocol should be followed if the sterility of a multi-dose vial is compromised?

The most appropriate action to take when the sterility of a multi-dose vial is compromised is to discard the vial immediately. Multi-dose vials are designed for multiple uses, but their integrity can be at risk if they are exposed to contaminants. This can occur through improper handling, needle accidents, or if the vial is not properly sealed after using.

When the sterility is compromised, using the contents can pose significant risks, including potential infections in patients caused by bacteria or other pathogens. Therefore, following strict infection control protocols is crucial to ensure patient safety. Disposing of the vial eliminates the risk of using compromised medication and upholds the standards of safe medication administration in healthcare settings.

Other options, such as continuing to use the vial until empty, transferring the contents to a new vial, or refrigerating it, do not address the primary concern—preventing infection from non-sterile solutions—and can lead to adverse outcomes.